The manufacturer considers the toxicological character, chemical structure and exposure levels of the product constituents for the human health for the safety evaluation in the final product. For this purpose, the certain exposure features are considered for the target group which the product is served for use or the area which the product will be applied. Special safety evaluation is necessary for the products used for the children younger than three years old and for the personal hygiene products to be applied externally to the external genital organs.

The name and address of the responsible or authorized person who will make this evaluation; this person should have a degree in pharmacy, veterinary, biology, chemistry, biochemistry, toxicology, microbiology, dermatology, medicine or an equivalent science branch and should have the enough experience.

A guide was published for the Safety Evaluation by the Turkish Drug and Medical Device Institution Cosmetic Products Coordination Department.